Diabetic Retinopathy: An Overview on Mechanisms, Pathophysiology and Pharmacotherapy

نویسندگان

چکیده

Diabetes mellitus is one of the most frequently occurring metabolic disorders (DMs), impairing healthy life around globe, with mild-to-severe secondary complications. DM associated complications, including diabetic retinopathy (DR), which damages retina and can lead to vision loss. Diabetic patients often suffer from extreme retinal capillary aneurysms, hemorrhage, edema, likely non-proliferative or proliferative (NPDR PDR) macular edema (DME). Several epidemiological studies have illustrated that occurrence DR vary by age diabetes onset, type, ethnicity. Although very well-known, complexity its etiology diagnosis makes therapeutic intervention difficult challenging. We reviewed different pathological aspects underlying mechanism occurrence. In this review, we aim provide an in-depth understanding illustration progression retinopathy, pathophysiology, epidemiology, prospective targets.

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ژورنال

عنوان ژورنال: Diabetology

سال: 2022

ISSN: ['2673-4540']

DOI: https://doi.org/10.3390/diabetology3010011